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What is the diagnosis for Opioid Intoxication?

A diagnosis of “opioid intoxication” is based on the recent use of an opioid with symptoms listed below. Opioids include heroin, fentanyl, and prescription pain relievers such as oxycodone (OxyContin), hydrocodone (Vicodin), codeine, morphine, and others. 

Symptoms of opioid intoxication include:

  • Significant problematic behavioral or psychological changes (e.g., initial euphoria followed by apathy, dysphoria, psychomotor agitation or retardation, impaired judgment) that developed during, or shortly after, opioid use.
  • Pupillary constriction and one or more of the following symptoms that developed during, or shortly after, opioid use:
    • Drowsiness or coma
    • Slurred speech
    • Impairment in attention or memory

The symptoms are not attributable to another medication condition or mental disorder, including intoxication with another substance.

Mental Health Library Sources:

Information included in all topics of the Mental Health Library comes from the Desk Reference to the Diagnostic Criteria From DSM-5 and Kaplan & Sadock’s Concise Textbook of Clinical Psychiatry. Complete diagnostic and treatment information may be found within these publications.


Information within the Mental Health Library is not intended to be used for self-diagnosis purposes. Rather, it is provided as a public educational service to make people aware of mental health conditions. Please consult a qualified mental health professional for a diagnosis of any suspected mental health illness.

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